Lytic effect of trypsin, lysozyme, and complement on Treponema pallidum.
نویسندگان
چکیده
R. H. JONES, T. A. NEVIN, W. J. GUEST, AND L. C. LOGAN From the Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48104, and the Venereal Disease Research Laboratory, Venereal Disease Program, National Communicable Disease Center, Bureau of Disease Prevention and Environmental Control, Public Health Service, U.S. Department of Health, Education, and Welfare, Atlanta, Georgia 30333, U.S.A.
منابع مشابه
Enhancement by lysozyme of the sensitivity of Treponema pallidum immobilization tests.
The addition of lysozyme to the survival medium has been shown (Metzger, Hardy, and Nell, 1961) to increase the rate of immobilization of Treponema pallidum by syphilitic serum and complement; this might allow T. pallidum immobilization (TPI) tests to be completed in a working day. But, more important from the point of view of diagnosis, was the possibility of increasing the sensitivity of the ...
متن کاملThe importance of different components of normal human serum and lysozyme in the rapid immobilisation of purified Treponema pallidum, Nichols strain.
OBJECTIVES To study the role of different components in normal human serum and the role of lysozyme in rapid immobilisation of Percoll purified T pallidum (Nichols). MATERIALS AND METHODS The immobilisation of Percoll purified T pallidum was studied after pre-incubations with different serum fractions (Fr) of normal human serum (Fr 1, containing IgM; Fr 2, containing IgG and a low level of ha...
متن کاملSpecific immunofluorescence staining of Treponema pallidum in smears and tissues.
To date, tissue sections prepared from Formalin-fixed tissues have not been successfully stained with Treponema pallidum subspecies-specific antibody in a direct fluorescent-antibody assay. While current methods stain T. pallidum, they do not distinguish T. pallidum from other spirochetes such as Borrelia burgdorferi (E. F. Hunter, P. W. Greer, B. L. Swisher, A. R. Simons, C. E. Farshy, J. A. C...
متن کاملThe surface of virulent Treponema pallidum: resistance to antibody binding in the absence of complement and surface association of recombinant antigen 4D.
The binding of immunoglobulin G present in syphilitic immune rabbit serum, syphilitic human serum, and rabbit antiserum to purified recombinant Treponema pallidum antigen 4D by T. pallidum, Nichols strain, was studied by immunoelectron microscopy. Treponemes were incubated with antiserum under the conditions of the T. pallidum immobilization test, in which T. pallidum-specific antibody renders ...
متن کاملEffect of dietary supplement of Spirulina platensis on immune indices complement and lysozyme of benny fish Mesopotamichthys sharpeyi (Günther, 1874)
Effects of different levels of spirulina dietary supplementation on some immune parameters of Benny Mesopotamichthys sharpeyi fingerlings were investigated in an 8 weeks experimental period. Dried and powdered spirulina algae in five levels of 0, 2.5, 5.0, 7.5 and 10.0 % was added to the experimental diet .Experimental fish were fed to satiation twice daily. Results indicated that the amount of...
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ورودعنوان ژورنال:
- The British journal of venereal diseases
دوره 44 3 شماره
صفحات -
تاریخ انتشار 1968